ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

SNP Report

Basic Info

Name	rs3813929 dbSNP Ensembl
Location	ChrX:113818520(Fwd)
Variant Alleles	C/T
Ancestral Allele	C
Functional Annotation	upstream_gene_variant.
Consequence to Transcript	upstream_gene_variant(ENST00000371950; ENST00000276198; ENST00000371951)
No. of Studies	2 (significant: 1; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Li J, 2006(a)	C/T		TDT P-value=0.045, X²=4.009 in ADHD; TDT P-value=...... TDT P-value=0.045, X²=4.009 in ADHD; TDT P-value=0.175, X²=1.841 in ADHD-C; TDT P-value=0.298, X²=1.085 in ADHD-I More...	a preferential transmission of the C allele to ADHD probands a preferential transmission of the C allele to ADHD probands	Significant
Xu X, 2009(a)	C-759T		TDT P-value=0.384, OR=1.2 TDT P-value=0.384, OR=1.2	no significant association with ADHD was found no significant association with ADHD was found	Non-significant

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
HTR2C	5-hydroxytryptamine (serotonin) receptor 2C	Xq24	5(2/3/0)

Genes from other sources (count: 0)

SNPs in LD with rs3813929 (count: 41) View in gBrowse (chrX:113776160..114000273 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 41)

rs_ID	Functional Annotation	r²[population]
rs493533		0.846[CHD]
rs11797955	downstream_gene_variant; intron_variant; upstream_gene_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs12690355	intron_variant	1.0[ASW]; 0.925[CEU]; 0.842[CHB]; 1.0[CHD]; 1.0[JPT]; 1.0[MEX]; 0.942[TSI]
rs12847225	intron_variant	0.885[CHD]
rs6643897	downstream_gene_variant; intron_variant	0.818[JPT]
rs17260565	intron_variant; upstream_gene_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs508865	upstream_gene_variant	0.803[CHD]
rs12860460	intron_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs12837651	intron_variant; upstream_gene_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs12855533	intron_variant	0.944[CHD]
rs498207	upstream_gene_variant	0.943[CHD]
rs12858300	intron_variant	1.0[ASW]
rs12833104	intron_variant	1.0[ASW]; 0.925[CEU]; 1.0[CHD]; 1.0[JPT]; 0.941[TSI]
rs12836204		0.842[CHB]
rs3813928	upstream_gene_variant	1.0[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 1.0[LWK]; 1.0[MEX]; 1.0[MKK]; 1.0[TSI]
rs12689838		0.8[CEU]; 0.86[CHB]
rs12686940		0.859[CEU]; 0.86[CHB]; 0.819[CHD]; 0.819[TSI]
rs12688309		0.825[CEU]; 0.859[CHB]
rs6644065	intron_variant	1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[JPT]; 1.0[MEX]; 0.941[TSI]
rs12845201	intron_variant	1.0[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[JPT]; 1.0[MEX]; 1.0[MKK]; 0.941[TSI]
rs3795182	upstream_gene_variant	0.925[CEU]; 1.0[CHB]; 1.0[JPT]
rs12858410	intron_variant	0.847[CEU]; 0.819[JPT]
rs7887868	intron_variant; upstream_gene_variant	0.944[CHD]
rs11798698	intron_variant	0.943[CHD]
rs7055144	downstream_gene_variant; intron_variant	0.944[CHD]
rs12836771	intron_variant; upstream_gene_variant	1.0[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[JPT]; 1.0[LWK]; 1.0[MEX]; 1.0[MKK]; 0.942[TSI]
rs12846241	intron_variant	1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[JPT]; 1.0[MEX]; 0.942[TSI]
rs547617		0.846[CHD]
rs4911871	downstream_gene_variant; intron_variant; upstream_gene_variant	0.8[CEU]; 0.819[JPT]; 0.84[TSI]
rs17326429	downstream_gene_variant; intron_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs11798460	intron_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs1581287		1.0[ASW]; 0.859[CEU]; 0.86[CHB]; 0.885[CHD]; 0.82[TSI]
rs12687644		0.859[CEU]; 0.86[CHB]
rs12854485	intron_variant	0.944[CHD]
rs521018	upstream_gene_variant	0.943[CHD]
rs12847764		0.859[CEU]; 0.86[CHB]
rs12836749	intron_variant	0.847[CEU]; 0.86[CHB]; 0.842[JPT]
rs12688871		1.0[ASW]; 0.925[CEU]; 1.0[CHB]; 0.944[CHD]; 0.87[GIH]; 0.85[LWK]; 0.885[MEX]; 0.942[TSI]
rs11798015		1.0[ASW]; 0.859[CEU]; 0.86[CHB]; 0.885[CHD]; 0.82[TSI]
rs12690135	intron_variant	1.0[ASW]; 0.925[CEU]; 0.86[CHB]; 1.0[CHD]; 1.0[JPT]; 1.0[LWK]; 1.0[MEX]; 0.811[MKK]; 0.942[TSI]
rs12689767	intron_variant; upstream_gene_variant	1.0[ASW]; 0.925[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[JPT]; 1.0[LWK]; 0.885[MEX]; 1.0[MKK]; 0.888[TSI]