ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

SNP Report

Basic Info

Name	rs2952151 dbSNP Ensembl
Location	Chr17:37828496(Fwd)
Variant Alleles	T/C
Ancestral Allele	T
Functional Annotation	3_prime_UTR_variant; downstream_gene_variant; nc_transcript_variant; non_coding_exon_variant.
Consequence to Transcript	3_prime_UTR_variant(ENST00000378011; ENST00000579146; ENST00000300658) downstream_gene_variant(ENST00000269582; ENST00000577337; ENST00000394246; ENST00000584620; ENST00000581428; ENST00000582276; ENST00000580898; ENST00000429199) nc_transcript_variant(ENST00000309862) non_coding_exon_variant(ENST00000309862)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Hawi, Z., 2012	C:T	C	P-value=0.7217, X²=0.13, OR=1.05, 95% CI=0.79-1.3...... P-value=0.7217, X²=0.13, OR=1.05, 95% CI=0.79-1.38 More...	The marker did not show significant association with ADHD. The marker did not show significant association with ADHD.	Non-significant

SNP related genes (count: 2)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
PNMT	phenylethanolamine N-methyltransferase	17q	3(2/1/0)

Genes from other sources (count: 1)

Approved Symbol	Approved Name	Location
PGAP3	post-GPI attachment to proteins 3	17q21.2

SNPs in LD with rs2952151 (count: 47) View in gBrowse (chr17:37770005..37884037 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

Literature-origin SNPs (count: 4)

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs1053651	downstream_gene_variant; synonymous_variant; upstream_gene_variant	1(0/1/0)	0.908[CHB]; 0.875[CHD]; 0.905[JPT]; 0.895[TSI]
rs879606	downstream_gene_variant; upstream_gene_variant	1(0/1/0)	0.822[JPT]
rs3764352	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	1(0/1/0)	0.822[JPT]
rs907094	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	1(0/1/0)	0.822[JPT]

LD-proxies (count: 43)

rs_ID	Functional Annotation	r²[population]
rs9972882	NMD_transcript_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.908[CHB]; 0.875[CHD]; 0.858[GIH]; 0.905[JPT]; 0.973[TSI]
rs881844	NMD_transcript_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.864[CHB]; 0.905[JPT]
rs903501	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.943[ASW]; 1.0[CEU]; 0.954[CHB]; 0.95[CHD]; 0.944[GIH]; 1.0[JPT]; 0.913[MEX]; 0.894[TSI]
rs11078919	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.906[CEU]; 0.954[CHB]; 0.95[CHD]; 1.0[JPT]; 0.829[MEX]
rs12150603	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.906[CEU]; 0.954[CHB]; 0.95[CHD]; 1.0[JPT]
rs12453682	upstream_gene_variant	0.825[TSI]
rs1877031	NMD_transcript_variant; downstream_gene_variant; missense_variant; nc_transcript_variant; non_coding_exon_variant; upstream_gene_variant	0.908[CHB]; 0.875[CHD]; 0.905[JPT]; 0.826[TSI]
rs2517958	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	0.906[CEU]; 0.903[CHB]; 1.0[JPT]
rs12150298	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.903[CEU]; 0.954[CHB]; 0.925[CHD]; 1.0[JPT]; 0.833[MEX]
rs1810132	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.898[CEU]; 0.83[CHB]; 0.875[CHD]; 0.971[GIH]; 0.915[MEX]
rs2271309	NMD_transcript_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.822[JPT]
rs1565922	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	0.861[CEU]; 0.954[CHB]; 0.95[CHD]; 1.0[GIH]; 1.0[JPT]; 0.956[MEX]; 0.815[MKK]; 0.974[TSI]
rs2934952	NMD_transcript_variant; intron_variant; nc_transcript_variant	1.0[CEU]
rs1874228	upstream_gene_variant	0.822[JPT]
rs2517955	NMD_transcript_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.864[CEU]; 0.87[CHB]; 0.899[CHD]; 0.953[JPT]; 0.877[MEX]
rs2941503	3_prime_UTR_variant; downstream_gene_variant; nc_transcript_variant; non_coding_exon_variant	1.0[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 0.971[GIH]; 1.0[JPT]; 0.935[LWK]; 0.957[MEX]; 0.945[MKK]; 1.0[TSI]; 0.964[YRI]
rs2941505	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.906[CEU]; 0.954[CHB]; 1.0[JPT]
rs10852934	downstream_gene_variant; upstream_gene_variant	0.822[JPT]
rs12940986	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	0.906[CEU]; 0.954[CHB]; 0.95[CHD]; 1.0[JPT]; 0.877[MEX]
rs2517956	NMD_transcript_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.943[ASW]; 0.951[CEU]; 0.87[CHB]; 0.899[CHD]; 0.917[GIH]; 0.953[JPT]; 0.872[MEX]; 0.867[TSI]
rs907089	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.906[CEU]; 0.954[CHB]; 0.95[CHD]; 1.0[JPT]
rs2517957	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	0.906[CEU]; 0.951[CHB]; 1.0[JPT]
rs9303274	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	0.906[CEU]; 0.954[CHB]; 0.95[CHD]; 1.0[JPT]; 0.877[MEX]
rs2517954	NMD_transcript_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.951[CEU]; 0.866[CHB]; 0.953[JPT]
rs931992	5_prime_UTR_variant; downstream_gene_variant; upstream_gene_variant	0.864[CHB]; 0.85[CHD]; 0.905[JPT]; 0.826[TSI]
rs2934971	downstream_gene_variant; intron_variant; upstream_gene_variant	0.901[CEU]; 0.83[CHB]; 0.899[CHD]; 0.971[GIH]; 0.875[MEX]; 0.842[TSI]
rs9675194	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.906[CEU]; 0.954[CHB]; 0.924[CHD]; 1.0[JPT]; 0.833[MEX]
rs11869286	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.908[CHB]; 0.875[CHD]; 0.902[JPT]; 0.826[TSI]
rs1058808	3_prime_UTR_variant; NMD_transcript_variant; downstream_gene_variant; feature_truncation; frameshift_variant; missense_variant; upstream_gene_variant	0.814[CEU]
rs2952155	NMD_transcript_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.83[CHB]
rs2934953	NMD_transcript_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 0.906[CHB]; 1.0[JPT]
rs1476278	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	0.906[CEU]; 0.954[CHB]; 0.95[CHD]; 1.0[JPT]; 0.877[MEX]
rs2941504	3_prime_UTR_variant; NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant; non_coding_exon_variant; synonymous_variant	0.943[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 0.957[MEX]; 0.864[MKK]; 1.0[TSI]; 0.825[YRI]
rs1565923	NMD_transcript_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.901[CEU]
rs8078228	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.899[CEU]; 0.951[CHB]; 1.0[JPT]
rs14050	3_prime_UTR_variant; downstream_gene_variant; nc_transcript_variant; non_coding_exon_variant	0.838[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.957[MEX]; 0.845[MKK]; 1.0[TSI]
rs2313171	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.896[CEU]; 0.857[CHB]; 1.0[JPT]
rs907087	3_prime_UTR_variant; downstream_gene_variant; nc_transcript_variant; non_coding_exon_variant	1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.955[MEX]; 1.0[TSI]
rs2247862	downstream_gene_variant; intron_variant; nc_transcript_variant	0.943[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.825[LWK]; 0.957[MEX]; 0.859[MKK]; 1.0[TSI]; 0.859[YRI]
rs2941506	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.899[CEU]; 0.949[CHB]; 0.946[JPT]
rs2271308	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant; non_coding_exon_variant; upstream_gene_variant	0.864[CHB]; 0.85[CHD]; 0.905[JPT]; 0.872[TSI]
rs903502	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	0.906[CEU]; 1.0[CHB]; 0.975[CHD]; 1.0[JPT]; 0.872[MEX]; 0.9[TSI]
rs2952156	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	0.901[CEU]