ADHDgene Database

Hot Results

Quick Search

Keyword:
Type:

Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

SNP Report

Basic Info

Name	rs174548 dbSNP Ensembl
Location	Chr11:61571348(Fwd)
Variant Alleles	C/G
Ancestral Allele	G
Functional Annotation	5_prime_UTR_variant; intron_variant; nc_transcript_variant.
Consequence to Transcript	5_prime_UTR_variant(ENST00000460649) intron_variant(ENST00000574708; ENST00000433932; ENST00000542506; ENST00000539999; ENST00000496123; ENST00000350997; ENST00000536991) nc_transcript_variant(ENST00000496123)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Brookes KJ, 2006(a)	C/G		allelic P-value=0.9, OR=1.02; TDT P-value=0.191, OR=0.73 (C ...... allelic P-value=0.9, OR=1.02; TDT P-value=0.191, OR=0.73 (C allele), OR=1.37 (G allele); HHRR P-value=0.24, OR=0.94 (C allele), OR=1.21 (G allele) More...	was not statistically significant was not statistically significant	Non-significant

SNP related genes (count: 2)

Literature-origin genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
FADS2	fatty acid desaturase 2	11q12.2	3(3/0/0)
FADS1	fatty acid desaturase 1	11q12-q13.1	3(1/2/0)

Genes from other sources (count: 0)

SNPs in LD with rs174548 (count: 29) View in gBrowse (chr11:61543499..61623140 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

Literature-origin SNPs (count: 1)

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs174545	3_prime_UTR_variant; downstream_gene_variant; intron_variant	1(0/1/0)	1.0[CHB]; 1.0[JPT]

LD-proxies (count: 28)

rs_ID	Functional Annotation	r²[population]
rs174541	downstream_gene_variant; intron_variant	1.0[CHB]; 1.0[JPT]
rs174538	5_prime_UTR_variant; NMD_transcript_variant; downstream_gene_variant; upstream_gene_variant	1.0[CHB]; 0.932[CHD]; 0.808[GIH]; 1.0[JPT]
rs174550	5_prime_UTR_variant; intron_variant; nc_transcript_variant	0.808[CEU]; 1.0[CHB]; 1.0[JPT]
rs174566	intron_variant; upstream_gene_variant	0.808[CEU]; 1.0[CHB]; 0.908[CHD]; 0.939[GIH]; 1.0[JPT]; 0.966[LWK]; 0.907[MEX]; 0.873[MKK]
rs1535	downstream_gene_variant; intron_variant; upstream_gene_variant	0.808[CEU]; 1.0[CHB]; 0.907[CHD]; 1.0[GIH]; 1.0[JPT]
rs4246215	3_prime_UTR_variant; downstream_gene_variant; intron_variant; upstream_gene_variant	1.0[CHB]; 0.931[CHD]; 0.939[GIH]; 1.0[JPT]
rs174547	downstream_gene_variant; intron_variant; nc_transcript_variant	0.808[CEU]; 1.0[CHB]; 0.931[CHD]; 1.0[GIH]; 1.0[JPT]
rs102275	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant; non_coding_exon_variant; upstream_gene_variant	0.804[CEU]; 1.0[CHB]; 0.932[CHD]; 0.834[GIH]; 1.0[JPT]; 0.863[MEX]
rs174556	NMD_transcript_variant; downstream_gene_variant; intron_variant; upstream_gene_variant	1.0[CEU]; 1.0[CHB]; 0.977[CHD]; 1.0[GIH]; 1.0[JPT]; 0.869[MEX]; 0.901[TSI]
rs174535	downstream_gene_variant; intron_variant; nc_transcript_variant; non_coding_exon_variant; synonymous_variant	0.808[CEU]; 1.0[CHB]; 0.908[CHD]; 1.0[JPT]
rs174528	intron_variant; nc_transcript_variant; upstream_gene_variant	1.0[CHB]; 1.0[JPT]
rs174549	5_prime_UTR_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.869[MEX]; 0.901[TSI]
rs174578	intron_variant; upstream_gene_variant	0.802[CEU]; 1.0[CHB]; 0.947[JPT]
rs174601	intron_variant; nc_transcript_variant; non_coding_exon_variant	1.0[CHB]; 0.81[JPT]
rs174583	intron_variant; nc_transcript_variant; upstream_gene_variant	0.808[CEU]; 0.95[CHB]; 0.906[CHD]; 0.873[GIH]; 0.863[MEX]
rs174536	downstream_gene_variant; intron_variant; nc_transcript_variant; non_coding_exon_variant	0.808[CEU]; 1.0[CHB]; 1.0[JPT]
rs174577	intron_variant; upstream_gene_variant	0.808[CEU]; 1.0[CHB]; 0.907[CHD]; 1.0[GIH]; 0.947[JPT]; 0.863[MEX]
rs509360	downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	1.0[CHB]; 0.864[CHD]; 1.0[JPT]
rs174534	downstream_gene_variant; intron_variant; nc_transcript_variant; non_coding_exon_variant	1.0[CHB]; 0.932[CHD]; 1.0[JPT]
rs174533	downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	1.0[CHB]; 1.0[JPT]
rs174568	3_prime_UTR_variant; intron_variant; synonymous_variant; upstream_gene_variant	0.808[CEU]; 1.0[CHB]; 0.908[CHD]; 1.0[GIH]; 1.0[JPT]
rs174546	3_prime_UTR_variant; downstream_gene_variant; intron_variant	0.808[CEU]; 1.0[CHB]; 0.932[CHD]; 1.0[GIH]; 1.0[JPT]
rs108499	intron_variant; nc_transcript_variant; upstream_gene_variant	1.0[CHB]; 0.932[CHD]; 0.808[GIH]; 1.0[JPT]
rs174555	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	1.0[CEU]; 1.0[CHB]; 0.977[CHD]; 1.0[GIH]; 1.0[JPT]; 0.869[MEX]; 0.901[TSI]
rs174576	intron_variant; upstream_gene_variant	0.808[CEU]; 1.0[CHB]; 0.908[CHD]; 1.0[GIH]; 0.947[JPT]; 0.863[MEX]
rs174570	downstream_gene_variant; intron_variant; upstream_gene_variant	1.0[CHB]; 0.908[CHD]; 1.0[JPT]
rs174537	downstream_gene_variant; intron_variant; nc_transcript_variant; non_coding_exon_variant	0.808[CEU]; 1.0[CHB]; 0.931[CHD]; 0.834[GIH]; 1.0[JPT]
rs174574	intron_variant; upstream_gene_variant	0.949[CHB]; 0.905[CHD]; 0.939[GIH]; 0.946[JPT]