ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0007173
Name	epidermal growth factor receptor signaling pathway
Type	Biological Process
No. of Genes in ADHDgene	25
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 25)

Literature-origin genes (count: 3)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
EREG	epiregulin	4q21.21	1(0/0/1)
ADRBK1	adrenergic, beta, receptor kinase 1	11q13	1(0/1/0)
GSK3B	glycogen synthase kinase 3 beta	3q13.3	1(1/0/0)

Genes from other sources (count: 22)

Approved Symbol	Approved Name	Source	Evidence[PMID]
MAPK3	mitogen-activated protein kinase 3	Mapped by CNV
SHC3	SHC (Src homology 2 domain containing) transforming protein 3	Mapped by significant region	TAS[8808684]
PLCE1	phospholipase C, epsilon 1	Mapped by PBA pathway	NAS[11022048]
PRKAR2B	protein kinase, cAMP-dependent, regulatory, type II, beta	Mapped by CNV
REPS2	RALBP1 associated Eps domain containing 2	Mapped by CNV	TAS[9422736]
BAD	BCL2-associated agonist of cell death	Mapped by significant region
ITPR2	inositol 1,4,5-trisphosphate receptor, type 2	Mapped by LD-proxy; Mapped by literature SNP
ITPR1	inositol 1,4,5-trisphosphate receptor, type 1	Mapped by CNV
NCK2	NCK adaptor protein 2	Mapped by PBA pathway	TAS[9737977]
RICTOR	RPTOR independent companion of MTOR, complex 2	Mapped by significant region
RPS6KB2	ribosomal protein S6 kinase, 70kDa, polypeptide 2	Mapped by significant region
ADCY4	adenylate cyclase 4	Mapped by significant region
UBC	ubiquitin C	Mapped by CNV
MAPK1	mitogen-activated protein kinase 1	Mapped by LD-proxy
UBB	ubiquitin B	Mapped by significant region
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	Mapped by significant region
BCAR1	breast cancer anti-estrogen resistance 1	Mapped by significant region
MAPKAP1	mitogen-activated protein kinase associated protein 1	Mapped by significant region
ADAM17	ADAM metallopeptidase domain 17	Mapped by significant region	IDA[12743035]
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	Mapped by LD-proxy	NAS[15504738]
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	Mapped by significant region
VIL1	villin 1	Mapped by significant region	IDA[17229814]