ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

SNP Report

Basic Info

Name	rs7305115 dbSNP Ensembl
Location	Chr12:72372862(Fwd)
Variant Alleles	A/G
Ancestral Allele	G
Functional Annotation	synonymous_variant.
Consequence to Transcript	synonymous_variant(ENST00000333850)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Johansson S, 2010			logistic regression P-value=0.24, OR=1.11; meta-analysis P-v...... logistic regression P-value=0.24, OR=1.11; meta-analysis P-value=0.9, OR=0.99 More...	no significant association no significant association	Non-significant

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
TPH2	tryptophan hydroxylase 2	12q15	10(7/3/0)

Genes from other sources (count: 0)

SNPs in LD with rs7305115 (count: 36) View in gBrowse (chr12:72342284..72406833 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

Literature-origin SNPs (count: 2)

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs7955501	NMD_transcript_variant; intron_variant	1(0/1/0)	0.915[CEU]
rs1352250	intron_variant	2(1/1/0)	0.917[CEU]; 0.86[JPT]

LD-proxies (count: 34)

rs_ID	Functional Annotation	r²[population]
rs4760754	intron_variant	1.0[CEU]; 0.954[CHB]; 0.901[CHD]; 0.977[GIH]; 0.953[JPT]; 0.878[MEX]; 1.0[TSI]
rs7967686	intron_variant	1.0[CEU]; 0.954[CHB]; 0.951[JPT]
rs2171363	downstream_gene_variant; intron_variant	1.0[CEU]; 1.0[CHB]; 0.952[CHD]; 1.0[GIH]; 0.909[JPT]; 0.837[MEX]; 1.0[TSI]
rs1843811	intron_variant	0.955[CEU]; 1.0[CHB]; 1.0[JPT]
rs11179033	intron_variant	0.953[JPT]
rs11179027	intron_variant	0.953[JPT]
rs6582073	intron_variant	1.0[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.957[MEX]; 0.881[MKK]; 1.0[TSI]; 0.87[YRI]
rs7309686	intron_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 1.0[YRI]
rs4760817	intron_variant	1.0[CEU]; 1.0[CHB]; 0.952[CHD]; 1.0[GIH]; 1.0[JPT]; 0.878[MEX]; 1.0[TSI]
rs4760816	intron_variant	0.941[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.978[LWK]; 0.957[MEX]; 1.0[MKK]; 1.0[TSI]; 1.0[YRI]
rs11179039	intron_variant	0.917[CEU]; 0.805[GIH]; 0.86[JPT]
rs11834097	intron_variant	0.953[JPT]
rs10879345	NMD_transcript_variant; intron_variant	1.0[CEU]; 1.0[CHB]; 0.93[CHD]; 1.0[GIH]; 0.909[JPT]; 0.84[MEX]; 0.91[TSI]
rs2368049	intron_variant	0.904[CEU]; 0.907[CHB]; 0.95[JPT]
rs4641528	intron_variant	1.0[CEU]; 0.954[CHB]; 0.903[CHD]; 1.0[GIH]; 0.953[JPT]; 0.878[MEX]; 1.0[TSI]
rs7969114	intron_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 0.849[YRI]
rs7963720	intron_variant	1.0[CEU]; 1.0[CHB]; 0.976[CHD]; 1.0[GIH]; 1.0[JPT]; 0.878[MEX]; 1.0[TSI]
rs11179002	NMD_transcript_variant; intron_variant	0.909[JPT]
rs6582077	intron_variant	1.0[ASW]; 1.0[CEU]; 0.954[CHB]; 1.0[CHD]; 0.978[GIH]; 0.953[JPT]; 0.881[MKK]; 1.0[TSI]; 0.82[YRI]
rs1532008	intron_variant	0.911[CHB]; 0.953[JPT]
rs11834114	intron_variant	0.953[JPT]
rs4760750	intron_variant	0.951[CEU]; 1.0[CHB]; 1.0[JPT]; 1.0[YRI]
rs7979770	intron_variant	1.0[CEU]; 0.911[CHB]; 0.953[JPT]
rs1386498	intron_variant	0.899[CEU]
rs12319219	intron_variant	0.953[JPT]
rs10879351	intron_variant	0.917[CEU]; 0.853[GIH]; 0.906[JPT]
rs17110532	intron_variant	0.85[JPT]
rs6582078	intron_variant	0.911[CEU]; 0.91[CHB]; 0.909[JPT]; 0.868[YRI]
rs12229394	intron_variant	0.953[JPT]
rs11179023	intron_variant	0.866[JPT]
rs10879346	NMD_transcript_variant; intron_variant	1.0[CEU]; 1.0[CHB]; 0.909[JPT]
rs10879350	intron_variant	0.953[JPT]
rs4760755	intron_variant	1.0[CEU]; 0.954[CHB]; 0.903[CHD]; 1.0[GIH]; 0.953[JPT]; 0.878[MEX]; 1.0[TSI]
rs12322900	NMD_transcript_variant; intron_variant	1.0[CEU]; 0.954[CHB]; 0.909[JPT]