ADHDgene Database

SNP Report

Basic Info

Name	rs650957 dbSNP Ensembl
Location	Chr1:191429227(Fwd)
Variant Alleles	C/T
Ancestral Allele	T
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Hinney, A., 2011		T	GWAS P-value=7.38E-05, OR=1.33, Replication FBAT P-value=0.5...... GWAS P-value=7.38E-05, OR=1.33, Replication FBAT P-value=0.5858, Combination P-value=1.34E-04 More...	This GWAS in a small group of clinically ascertained young G...... This GWAS in a small group of clinically ascertained young German patients with ADHD and population-based controls did not reveal genome-wide significant findings. Replication attempts in further German and international samples did also not lead to a P-value(s) below 5E-08. More...	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
RGS18	regulator of G-protein signaling 18	1q31.2	1(0/1/0)

SNPs in LD with rs650957 (count: 2) View in gBrowse (chr1:191428729..191429227 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs6666273		0.833[MEX]
rs648685		1.0[CEU]; 0.825[CHB]