ADHDgene Database

SNP Report

Basic Info

Name	rs521674 dbSNP Ensembl
Location	Chr10:112835590(Fwd)
Variant Alleles	T/A
Ancestral Allele	T
Functional Annotation	upstream_gene_variant.
Consequence to Transcript	upstream_gene_variant(ENST00000280155)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Hawi, Z., 2012	A:T	A	P-value=0.3494, X²=0.88, OR=1.14, 95% CI=0.86-1.5...... P-value=0.3494, X²=0.88, OR=1.14, 95% CI=0.86-1.51 More...	The marker did not show significant association with ADHD. The marker did not show significant association with ADHD.	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
ADRA2A	adrenergic, alpha-2A-, receptor	10q24-q26	12(4/8/0)

SNPs in LD with rs521674 (count: 11) View in gBrowse (chr10:112712477..112857971 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.


rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]
rs602618	downstream_gene_variant	1(0/1/0)	0.95[CEU]; 1.0[CHB]; 1.0[JPT]

rs_ID	Functional Annotation	r²[population]
rs4597005	intron_variant; nc_transcript_variant	0.873[YRI]
rs7908645		0.837[JPT]; 1.0[YRI]
rs10885068	intron_variant; nc_transcript_variant	0.833[JPT]; 0.837[YRI]
rs12416020	downstream_gene_variant	0.952[CEU]; 1.0[YRI]
rs745557		0.836[JPT]
rs638019	upstream_gene_variant	0.95[CHB]; 1.0[JPT]
rs11195400	intron_variant; nc_transcript_variant	0.829[YRI]
rs10885079		0.95[CEU]; 1.0[YRI]
rs7075626		1.0[YRI]
rs10885074	downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.829[YRI]