ADHDgene Database

SNP Report

Basic Info

Name	rs478597 dbSNP Ensembl
Location	Chr12:117751425(Fwd)
Variant Alleles	G/-/A
Ancestral Allele	G
Functional Annotation	feature_truncation; intron_variant.
Consequence to Transcript	feature_truncation(ENST00000344089; ENST00000317775; ENST00000338101) intron_variant(ENST00000344089; ENST00000317775; ENST00000338101)
No. of Studies	1 (significant: 0; non-significant: 0; trend: 1)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Lasky-Su J, 2008			P-value=8.08E-06 under Additive model for FBAT-PC IA symptom...... P-value=8.08E-06 under Additive model for FBAT-PC IA symptoms More...	association finding with P-value association finding with P-value	Trend

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
NOS1	nitric oxide synthase 1 (neuronal)	12q14-qter	1(1/0/0)

SNPs in LD with rs478597 (count: 14) View in gBrowse (chr12:117712186..117770982 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs567581	intron_variant	0.827[CEU]; 1.0[CHB]; 0.834[JPT]
rs4767529	intron_variant	0.823[CEU]
rs553715	intron_variant	0.811[CEU]; 1.0[CHB]
rs1607817	intron_variant	0.832[CEU]; 0.81[TSI]
rs561712	intron_variant	1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 0.915[JPT]; 1.0[MEX]; 1.0[TSI]
rs551846	intron_variant	0.851[CEU]
rs816293	intron_variant	0.829[CEU]; 0.825[GIH]
rs7309163	intron_variant	0.832[CEU]; 0.858[TSI]
rs530393	intron_variant	1.0[CEU]; 0.944[CHB]; 0.919[JPT]
rs549098	intron_variant	0.87[CEU]; 1.0[CHB]
rs570234	intron_variant; nc_transcript_variant; upstream_gene_variant	0.833[CEU]
rs539291	intron_variant	1.0[CEU]; 1.0[CHB]; 0.933[CHD]; 0.952[GIH]; 0.92[JPT]
rs3825102	intron_variant	0.832[CEU]
rs2293052	intron_variant	0.832[CEU]