ADHDgene Database

SNP Report

Basic Info

Name	rs4732641 dbSNP Ensembl
Location	Chr8:26617904(Fwd)
Variant Alleles	A/C
Ancestral Allele	A
Functional Annotation	NMD_transcript_variant; intron_variant.
Consequence to Transcript	NMD_transcript_variant(ENST00000519096; ENST00000521711) intron_variant(ENST00000380582; ENST00000519229; ENST00000519096; ENST00000380586; ENST00000521711; ENST00000380587; ENST00000380581)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Hawi, Z., 2012	A:C	C	P-value=0.3195, X²=0.99, OR=1.14, 95% CI=0.88-1.4...... P-value=0.3195, X²=0.99, OR=1.14, 95% CI=0.88-1.48 More...	The marker did not show significant association with ADHD. The marker did not show significant association with ADHD.	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
ADRA1A	adrenergic, alpha-1A-, receptor	8p21.2	3(2/1/0)

SNPs in LD with rs4732641 (count: 6) View in gBrowse (chr8:26613408..26648746 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs4236678	NMD_transcript_variant; intron_variant	0.812[CEU]; 0.916[MEX]; 0.847[TSI]
rs3802241	3_prime_UTR_variant; NMD_transcript_variant; downstream_gene_variant; intron_variant	0.916[MEX]; 0.829[TSI]
rs3739215	NMD_transcript_variant; downstream_gene_variant; intron_variant	0.812[CEU]; 0.916[MEX]; 0.848[TSI]
rs2036109	NMD_transcript_variant; intron_variant	1.0[ASW]; 0.958[CEU]; 1.0[CHB]; 0.977[CHD]; 1.0[GIH]; 0.953[JPT]; 1.0[LWK]; 1.0[MEX]; 0.972[MKK]; 1.0[TSI]; 1.0[YRI]
rs4732652	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.847[CHD]
rs17055939	NMD_transcript_variant; intron_variant	1.0[CEU]; 1.0[CHB]; 0.95[JPT]; 1.0[YRI]