ADHDgene Database

SNP Report

Basic Info

Name	rs3776581 dbSNP Ensembl
Location	Chr5:36661944(Fwd)
Variant Alleles	A/G
Ancestral Allele	A
Functional Annotation	downstream_gene_variant; intron_variant; nc_transcript_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000510740) intron_variant(ENST00000514563; ENST00000265113; ENST00000509272; ENST00000427100; ENST00000381918) nc_transcript_variant(ENST00000514563; ENST00000509272)
No. of Studies	2 (significant: 0; non-significant: 2; trend: 0)
Source	Literature-origin

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Laurin N, 2008(a)	G/A		P-value=0.574 in the catergorical analysis, P-value>0.05 in ...... P-value=0.574 in the catergorical analysis, P-value>0.05 in the quantitative analysis More...	no significant evidence of association no significant evidence of association	Non-significant
Turic D, 2005(a)	A/G		P-value=0.09 for pooled genotyping; allelic TRANSMIT P-value...... P-value=0.09 for pooled genotyping; allelic TRANSMIT P-value=0.06, X²=3.25 More...	a trend for association with A allele a trend for association with A allele	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3	5p13	2(1/1/0)

SNPs in LD with rs3776581 (count: 2) View in gBrowse (chr5:36659084..36663651 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs4869685	intron_variant; nc_transcript_variant	0.853[ASW]; 0.843[CEU]; 0.846[CHB]; 0.892[CHD]; 0.948[GIH]; 1.0[JPT]; 0.903[MEX]
rs1971720	downstream_gene_variant; intron_variant; nc_transcript_variant	0.888[CHB]