ADHDgene Database

SNP Report

Basic Info

Name	rs3756450 dbSNP Ensembl
Location	Chr5:1448148(Fwd)
Variant Alleles	A/G
Ancestral Allele	A
Functional Annotation	upstream_gene_variant.
Consequence to Transcript	upstream_gene_variant(ENST00000453492; ENST00000270349)
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Friedel S, 2007	T/C	T	FAMHAP P-value=0.03 in single marker association analysis FAMHAP P-value=0.03 in single marker association analysis	not significantly associated with ADHD after multiple test c...... not significantly associated with ADHD after multiple test correction More...	Significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	5p15.3	68(42/25/1)

SNPs in LD with rs3756450 (count: 4) View in gBrowse (chr5:1448148..1466919 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs2277006	NMD_transcript_variant; nc_transcript_variant; non_coding_exon_variant; synonymous_variant	0.858[CHB]; 0.953[CHD]; 0.81[GIH]
rs9728	3_prime_UTR_variant; NMD_transcript_variant; nc_transcript_variant; non_coding_exon_variant	0.93[CEU]; 0.892[CHB]; 0.95[JPT]
rs12654851	downstream_gene_variant	0.933[CEU]; 0.887[CHD]; 0.976[GIH]; 1.0[JPT]; 0.831[MEX]; 1.0[TSI]
rs2292023	3_prime_UTR_variant; NMD_transcript_variant; downstream_gene_variant	0.933[CEU]; 0.857[CHB]; 0.931[CHD]; 1.0[GIH]; 0.823[JPT]; 0.955[MEX]; 0.871[TSI]