ADHDgene Database

SNP Report

Basic Info

Name	rs2550956 dbSNP Ensembl
Location	Chr5:1447841(Fwd)
Variant Alleles	G/A
Ancestral Allele	G
Functional Annotation	upstream_gene_variant.
Consequence to Transcript	upstream_gene_variant(ENST00000513308; ENST00000270349; ENST00000453492)
No. of Studies	2 (significant: 0; non-significant: 2; trend: 0)
Source	Literature-origin

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Friedel S, 2007	C/T	T	FAMHAP P-value=0.66 in single marker association analysis FAMHAP P-value=0.66 in single marker association analysis	No association was found with ADHD No association was found with ADHD	Non-significant
Langley K, 2005	T/C		TDT P-value=0.55, Z-statistic=0.37 TDT P-value=0.55, Z-statistic=0.37	not significantly associated with ADHD in family-based analy...... not significantly associated with ADHD in family-based analysis More...	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	5p15.3	68(42/25/1)

SNPs in LD with rs2550956 (count: 9) View in gBrowse (chr5:1443498..1477310 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs2550948	upstream_gene_variant	2(2/0/0)	0.851[CHB]; 0.904[JPT]
rs2937639	intron_variant; upstream_gene_variant	1(0/1/0)	0.851[CHB]

rs_ID	Functional Annotation	r²[population]
rs31491	NMD_transcript_variant; downstream_gene_variant; intron_variant	0.843[ASW]; 0.835[CHB]; 0.884[MKK]
rs27052	NMD_transcript_variant; intron_variant; upstream_gene_variant	0.843[ASW]; 0.835[CHB]; 1.0[JPT]; 0.834[MKK]
rs2078247	downstream_gene_variant	0.873[CEU]; 0.833[CHB]; 1.0[JPT]
rs27053	NMD_transcript_variant; intron_variant; upstream_gene_variant	0.843[ASW]; 0.835[CHB]; 1.0[JPT]; 0.834[MKK]
rs2455391	intron_variant; upstream_gene_variant	0.843[ASW]; 0.92[CHB]; 1.0[JPT]; 0.866[TSI]
rs27056	NMD_transcript_variant; intron_variant	0.843[ASW]; 0.835[CHB]; 1.0[JPT]; 0.884[MKK]
rs8352	3_prime_UTR_variant; NMD_transcript_variant; nc_transcript_variant; non_coding_exon_variant	0.936[CEU]; 0.835[CHB]; 1.0[JPT]