ADHDgene Database

SNP Report

Basic Info

Name	rs2345039 dbSNP Ensembl
Location	Chr4:62765030(Fwd)
Variant Alleles	G/C
Ancestral Allele	G
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000512091; ENST00000509896; ENST00000514591; ENST00000511324; ENST00000507164; ENST00000506700; ENST00000507625; ENST00000508693; ENST00000514157; ENST00000504896; ENST00000508946; ENST00000506720; ENST00000514996; ENST00000502815; ENST00000506746; ENST00000545650; ENST00000570545; ENST00000577151; ENST00000574919; ENST00000573738; ENST00000574812; ENST00000576325; ENST00000572342; ENST00000573960; ENST00000572079; ENST00000576469; ENST00000574839; ENST00000576028; ENST00000573720; ENST00000571630; ENST00000574536)
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Arcos-Burgos M, 2010	C:G		fixed-effects meta-analysis P-value= 8.97E-04, OR=1.21 fixed-effects meta-analysis P-value= 8.97E-04, OR=1.21	reaching significance at the meta-analysis after 10 000 perm...... reaching significance at the meta-analysis after 10 000 permutations More...	Significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
LPHN3	latrophilin 3	4q13.1	4(3/0/1)

SNPs in LD with rs2345039 (count: 6) View in gBrowse (chr4:62759270..62766992 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs11131347	intron_variant; upstream_gene_variant	0.95[CEU]
rs1376309	intron_variant	1.0[CEU]
rs1376310	intron_variant	0.95[CEU]
rs1450900	intron_variant	1.0[CEU]
rs7695892	intron_variant	0.955[CEU]
rs7690962	intron_variant	1.0[CEU]