ADHDgene Database

SNP Report

Basic Info

Name	rs1728818 dbSNP Ensembl
Location	Chr3:11032992(Fwd)
Variant Alleles	C/G
Ancestral Allele	G
Functional Annotation	upstream_gene_variant.
Consequence to Transcript	upstream_gene_variant(ENST00000462473; ENST00000287766; ENST00000425938)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Brookes K, 2006	C/G		UNPHASED TDT P-value=0.143; WHAP TDT P-value=0.050 UNPHASED TDT P-value=0.143; WHAP TDT P-value=0.050	possible association was observed in WHAP analysis possible association was observed in WHAP analysis	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
SLC6A1	solute carrier family 6 (neurotransmitter transporter, GABA), member 1	3p25-p24	1(0/1/0)

SNPs in LD with rs1728818 (count: 9) View in gBrowse (chr3:11021064..11037778 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.


rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]
rs2601126	intron_variant; nc_transcript_variant	1(1/0/0)	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 1.0[YRI]

rs_ID	Functional Annotation	r²[population]
rs2675156	upstream_gene_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 0.964[YRI]
rs2697148	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs2697150	intron_variant; nc_transcript_variant	0.929[YRI]
rs13325776		0.858[YRI]
rs2697149	intron_variant; nc_transcript_variant	0.929[YRI]
rs1710873	upstream_gene_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 1.0[YRI]
rs1728816	intron_variant; nc_transcript_variant	0.936[CEU]
rs1710898	intron_variant; nc_transcript_variant	0.955[CEU]; 1.0[CHB]; 1.0[JPT]; 1.0[YRI]