ADHDgene Database

SNP Report

Basic Info

Name	rs1370868 dbSNP Ensembl
Location	Chr10:132984356(Fwd)
Variant Alleles	G/A
Ancestral Allele	A
Functional Annotation	intron_variant; nc_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000368642; ENST00000483040) nc_transcript_variant(ENST00000483040)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Neale BM, 2010 (b)	A:G		GLM P-value=1.07E-05, meta-analysis P-value=0.2392 GLM P-value=1.07E-05, meta-analysis P-value=0.2392	One of the top 100 SNPs from imputed IMAGE II dataset One of the top 100 SNPs from imputed IMAGE II dataset	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
TCERG1L	transcription elongation regulator 1-like	10q26.3	1(0/0/1)

SNPs in LD with rs1370868 (count: 7) View in gBrowse (chr10:132983821..132993796 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs2033791	intron_variant; nc_transcript_variant	1(0/0/1)	0.855[CEU]; 1.0[CHB]; 1.0[CHD]; 0.901[GIH]; 1.0[JPT]
rs1583670	intron_variant; nc_transcript_variant	1(0/1/0)	0.93[CEU]; 0.888[CHB]; 0.899[CHD]; 0.824[JPT]; 0.91[MEX]; 0.93[TSI]
rs11593241	intron_variant; nc_transcript_variant	1(0/0/1)	0.855[CEU]; 1.0[CHB]; 1.0[CHD]; 0.901[GIH]; 1.0[JPT]
rs2397752	intron_variant; nc_transcript_variant	1(0/1/0)	0.888[CHB]; 0.843[CHD]; 0.824[JPT]

rs_ID	Functional Annotation	r²[population]
rs11594799	intron_variant; nc_transcript_variant	0.835[CEU]; 1.0[CHB]; 1.0[JPT]
rs1583669	intron_variant; nc_transcript_variant	0.922[CEU]; 0.888[CHB]; 0.817[JPT]
rs12249515	intron_variant; nc_transcript_variant	1.0[CHB]; 1.0[JPT]