ADHDgene Database

SNP Report

Basic Info

Name	rs13274396 dbSNP Ensembl
Location	Chr8:26716205(Fwd)
Variant Alleles	C/T
Ancestral Allele	C
Functional Annotation	NMD_transcript_variant; downstream_gene_variant; intron_variant; upstream_gene_variant.
Consequence to Transcript	NMD_transcript_variant(ENST00000521711; ENST00000519096) downstream_gene_variant(ENST00000358857) intron_variant(ENST00000521711; ENST00000276393; ENST00000380586; ENST00000519229; ENST00000354550; ENST00000380582; ENST00000519096; ENST00000380573; ENST00000380572; ENST00000380581; ENST00000380587) upstream_gene_variant(ENST00000518810; ENST00000518621)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Hawi, Z., 2012	T:C	T	P-value=0.3098, X²=1.03, OR=1.16, 95% CI=0.87-1.5...... P-value=0.3098, X²=1.03, OR=1.16, 95% CI=0.87-1.54 More...	The marker did not show significant association with ADHD. The marker did not show significant association with ADHD.	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
ADRA1A	adrenergic, alpha-1A-, receptor	8p21.2	3(2/1/0)

SNPs in LD with rs13274396 (count: 3) View in gBrowse (chr8:26714874..26720893 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs13278849	NMD_transcript_variant; downstream_gene_variant; intron_variant; upstream_gene_variant	0.943[ASW]; 0.956[CEU]; 0.864[GIH]; 0.862[MEX]; 0.893[MKK]; 0.956[YRI]
rs4732682	NMD_transcript_variant; intron_variant	0.911[YRI]
rs4732958	NMD_transcript_variant; intron_variant	0.943[ASW]; 0.863[MEX]; 0.879[MKK]; 0.864[TSI]; 0.956[YRI]