ADHDgene Database

SNP Report

Basic Info

Name	rs1176717 dbSNP Ensembl
Location	Chr11:113855342(Fwd)
Variant Alleles	C/A
Ancestral Allele	C
Functional Annotation	NMD_transcript_variant; intron_variant; nc_transcript_variant.
Consequence to Transcript	NMD_transcript_variant(ENST00000510849) intron_variant(ENST00000355556; ENST00000504030; ENST00000535865; ENST00000375498; ENST00000502622; ENST00000510849; ENST00000299961; ENST00000506841) nc_transcript_variant(ENST00000502622)
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Ribases M, 2009(b)			Case-control test: lowest P-value=0.027 for genotype analysi...... Case-control test: lowest P-value=0.027 for genotype analysis, P-value=0.078 for allele analysis in adult inattentive ADHD. More...	no significance after correcting for multiple comparisons no significance after correcting for multiple comparisons	Significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
HTR3A	5-hydroxytryptamine (serotonin) receptor 3A	11q23.1-q23.2	1(0/1/0)

SNPs in LD with rs1176717 (count: 2) View in gBrowse (chr11:113854679..113860425 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs1176713	3_prime_UTR_variant; NMD_transcript_variant; downstream_gene_variant; synonymous_variant	1.0[CEU]; 0.863[CHB]; 0.937[JPT]
rs11214796	NMD_transcript_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]