ADHDgene Database

SNP Report

Basic Info

Name	rs10953766 dbSNP Ensembl
Location	Chr7:114313218(Fwd)
Variant Alleles	A/G
Ancestral Allele	G
Functional Annotation	NMD_transcript_variant; downstream_gene_variant; intron_variant.
Consequence to Transcript	NMD_transcript_variant(ENST00000412402; ENST00000441290) downstream_gene_variant(ENST00000393500) intron_variant(ENST00000412402; ENST00000350908; ENST00000408937; ENST00000441290; ENST00000393494; ENST00000393489; ENST00000393498; ENST00000393491; ENST00000403559)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Ribases, M., 2012			P-value=0.47 in 643 adult attention-deficit/hyperactivity di...... P-value=0.47 in 643 adult attention-deficit/hyperactivity disorder patients and and 619 unrelated controls from Germany; P-value=0.16, OR (95% CI)=- in 431 combined attention-deficit/hyperactivity disorder patients and 619 unrelated controls from Germany More...	No significant association was found. No significant association was found.	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
FOXP2	forkhead box P2	7q31	1(1/0/0)

SNPs in LD with rs10953766 (count: 12) View in gBrowse (chr7:114303189..114366979 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs776467		0.811[JPT]
rs626593		0.819[CEU]
rs588331		0.827[CEU]
rs623127		0.827[CEU]
rs12705979	downstream_gene_variant	1.0[CHB]; 0.951[JPT]
rs592049		0.819[CEU]
rs650512		0.827[CEU]
rs17291908	NMD_transcript_variant; intron_variant	1.0[CHB]; 1.0[JPT]
rs1563408	NMD_transcript_variant; intron_variant	1.0[CHB]; 1.0[JPT]
rs4730639		0.819[CEU]; 0.811[JPT]
rs7795485	downstream_gene_variant	0.852[CEU]; 0.811[JPT]
rs11769707	downstream_gene_variant	0.819[CEU]