ADHDgene Database
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Type:
  • Large-scale studies
  • Data Summary
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

KEGG Pathway Report

Basic Info
ID hsa03430
Name Mismatch repair
Description  DNA mismatch repair (MMR) is a highly conserved biological pathway that plays a key role in maintaining genomic stability. MMR corrects DNA mismatches generated during DNA replication, thereby preventing mutations from becoming permanent in dividing cells. MMR also suppresses homologous recombination and was recently shown to play a role in DNA damage signaling. Defects in MMR are associated with genome-wide instability, predisposition to certain types of cancer including HNPCC, resistance to certain chemotherapeutic agents, and abnormalities in meiosis and sterility in mammalian systems.
No. of Genes in ADHDgene  2
Source Pathway by Database Search

Pathway related genes in ADHDgene (count: 2)

Literature-origin genes (count: 0)

Genes from other sources Help(count: 2)

Approved Symbol Approved Name Location Source
POLD3 polymerase (DNA-directed), delta 3, accessory subunit 11q14 Mapped by significant region
POLD4 polymerase (DNA-directed), delta 4 11q13 Mapped by significant region

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback
Last update: Feb 26, 2014