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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Other Variant Report

Basic Info

Name	SLC6A2_promoter_-3081A/T
Type	point mutation
Location	promoter
Related Gene	SLC6A2
No. of Study	3 (significant: 2; non-significant 1; trend: 0)

Variant related studies (count: 3)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Kim CH, 2006			frequency of -3081(T) allele, P-value=0.008, OR=2.00, X^...... frequency of -3081(T) allele, P-value=0.008, OR=2.00, X²=7.07; logistic regression results for the linear trend contrasting the number of T alleles: P-value=0.011, R²=0.06, X²=6.49 More...	a significant association was observed a significant association was observed	Significant
Cho SC, 2008	A/T		allelic TDT P-value=0.160, genotypic TDT P-value=0.339 allelic TDT P-value=0.160, genotypic TDT P-value=0.339	there was no evidence for biased transmission of any of the ...... there was no evidence for biased transmission of any of the alleles More...	Non-significant
Joung Y, 2010	A/T		logistic regression P-value=0.02, X²=5.60 in the ...... logistic regression P-value=0.02, X²=5.60 in the allele frequencies, OR=1.59 for T allele; logistic regression P-value=0.02, X²=7.1 in the genotype frequencies, OR=4.57 for TT and OR=1.96 for AT More...	provided further evidence of association provided further evidence of association	Significant