ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0005578
Name	proteinaceous extracellular matrix
Type	Cellular Component
No. of Genes in ADHDgene	47
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 47)

Literature-origin genes (count: 5)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
GPC6	glypican 6	13q32	1(0/0/1)
GPC5	glypican 5	13q32	1(0/0/1)
MMP7	matrix metallopeptidase 7 (matrilysin, uterine)	11q21-q22	1(0/0/1)
MMP24	matrix metallopeptidase 24 (membrane-inserted)	20q11.2	1(0/0/1)
VEGFA	vascular endothelial growth factor A	6p12	1(0/1/0)	NAS[14570917]

Genes from other sources (count: 42)

Approved Symbol	Approved Name	Source	Evidence[PMID]
TNN	tenascin N	Mapped by significant region
ADAMTS7	ADAM metallopeptidase with thrombospondin type 1 motif, 7	Mapped by LD-proxy
ZP4	zona pellucida glycoprotein 4	Mapped by CNV
WNT6	wingless-type MMTV integration site family, member 6	Mapped by significant region
WNT10A	wingless-type MMTV integration site family, member 10A	Mapped by significant region
DGCR6	DiGeorge syndrome critical region gene 6	Mapped by CNV	TAS[8733130]
TECTA	tectorin alpha	Mapped by significant region
ADAMTS8	ADAM metallopeptidase with thrombospondin type 1 motif, 8	Mapped by significant region
OGN	osteoglycin	Mapped by significant region
FN1	fibronectin 1	Mapped by significant region
MMP11	matrix metallopeptidase 11 (stromelysin 3)	Mapped by CNV
FLRT3	fibronectin leucine rich transmembrane protein 3	Mapped by CNV	NAS[10644439]
MMP13	matrix metallopeptidase 13 (collagenase 3)	Mapped by significant region
MMP8	matrix metallopeptidase 8 (neutrophil collagenase)	Mapped by significant region
ZP2	zona pellucida glycoprotein 2 (sperm receptor)	Mapped by significant region
MMP12	matrix metallopeptidase 12 (macrophage elastase)	Mapped by significant region
FLRT1	fibronectin leucine rich transmembrane protein 1	Mapped by significant region	NAS[10644439]
MMP1	matrix metallopeptidase 1 (interstitial collagenase)	Mapped by significant region
COCH	coagulation factor C homolog, cochlin (Limulus polyphemus)	Mapped by significant region
LTBP1	latent transforming growth factor beta binding protein 1	Mapped by CNV	NAS[8537398]
CD248	CD248 molecule, endosialin	Mapped by significant region	TAS[10947988]
ADAMTS12	ADAM metallopeptidase with thrombospondin type 1 motif, 12	Mapped by significant region
ZG16	zymogen granule protein 16 homolog (rat)	Mapped by CNV
SPOCK3	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3	Mapped by CNV; Mapped by LD-proxy; Mapped by literature SNP
OMD	osteomodulin	Mapped by significant region
ADAMTS15	ADAM metallopeptidase with thrombospondin type 1 motif, 15	Mapped by significant region
MMP16	matrix metallopeptidase 16 (membrane-inserted)	Mapped by CNV
ASPN	asporin	Mapped by significant region	IDA[17827158]
ZP1	zona pellucida glycoprotein 1 (sperm receptor)	Mapped by significant region
ADAMTS18	ADAM metallopeptidase with thrombospondin type 1 motif, 18	Mapped by CNV; Mapped by significant region
PRSS36	protease, serine, 36	Mapped by CNV
MMP27	matrix metallopeptidase 27	Mapped by significant region
CHL1	cell adhesion molecule with homology to L1CAM (close homolog of L1)	Mapped by CNV
ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2	Mapped by CNV; Mapped by literature SNP
WNT11	wingless-type MMTV integration site family, member 11	Mapped by significant region
ECM2	extracellular matrix protein 2, female organ and adipocyte specific	Mapped by significant region	TAS[9790758]
MMP10	matrix metallopeptidase 10 (stromelysin 2)	Mapped by significant region
TNR	tenascin R (restrictin, janusin)	Mapped by significant region
CTGF	connective tissue growth factor	Mapped by significant region
OTOA	otoancorin	Mapped by significant region
MMP3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)	Mapped by significant region
MMP20	matrix metallopeptidase 20	Mapped by significant region