ADHDgene Database

Gene Report

Basic Info

Approved Symbol	RIT2
Previous Symbol	RIN
Symbol Alias	RIBA
Approved Name	Ras-like without CAAX 2
Previous Name	Ric (Drosophila)-like, expressed in neurons
Location	18q12.3
Position	chr18:40323192-40695657, -
External Links	HGNC: 10017 Entrez Gene: 6014 Ensembl: ENSG00000152214 UCSC: uc002lav.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
18q11.2-12.3	chr18:19000000-43500000	1 (1/0/0)

Gene related GO terms (count: 9)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0003924	GTPase activity	Molecular Function	NAS[8824319]	41
GO:0005516	calmodulin binding	Molecular Function		32
GO:0007264	small GTPase mediated signal transduction	Biological Process	NAS[8824319]	58
GO:0007268	synaptic transmission	Biological Process	TAS[8918462]	96
GO:0048011	nerve growth factor receptor signaling pathway	Biological Process		42
GO:0005525	GTP binding	Molecular Function		53
GO:0005634	nucleus	Cellular Component		770
GO:0005886	plasma membrane	Cellular Component	TAS[8824319]	772
GO:0007165	signal transduction	Biological Process	TAS[8918462]	171

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with RIT2 (count: 3)

Gene Symbol	Pathway Count	Pathway List
RASD1	6	GTPase activity; small GTPase mediated signal transduction; GTP binding; nucleus; plasma membrane; signal transduction;
GNAL	5	GTPase activity; synaptic transmission; GTP binding; plasma membrane; signal transduction;
MAPK1	5	small GTPase mediated signal transduction; synaptic transmission; nerve growth factor receptor signaling pathway; nucleus; signal transduction;

Genes shared at least 2 KEGG pathways with RIT2 (count: 0)

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Region: chr18:40323192..40695657 View in gBrowse