ADHDgene Database

Gene Report

Basic Info

Approved Symbol	PPEF2
Symbol Alias	PPP7CB
Approved Name	protein phosphatase, EF-hand calcium binding domain 2
Name Alias	protein phosphatase 7, catalytic subunit, beta isozyme
Location	4q21.1
Position	chr4:76781001-76823724, -
External Links	HGNC: 9244 Entrez Gene: 5470 Ensembl: ENSG00000156194 UCSC: uc003hix.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Williams[2010]_43	chr4:75931128-77058132 (NCBI Build 36.1 (hg18))	1076977	4q13.3-4q21.1	Gain	Paternal

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 18)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0010801	negative regulation of peptidyl-threonine phosphorylation	Biological Process		1
GO:0030145	manganese ion binding	Molecular Function		10
GO:0030544	Hsp70 protein binding	Molecular Function		6
GO:0031435	mitogen-activated protein kinase kinase kinase binding	Molecular Function		7
GO:0005515	protein binding	Molecular Function	IPI[12051765]	910
GO:0005737	cytoplasm	Cellular Component		690
GO:0006470	protein dephosphorylation	Biological Process	TAS[9326663]	18
GO:0007601	visual perception	Biological Process		30
GO:0051879	Hsp90 protein binding	Molecular Function		4
GO:0043405	regulation of MAP kinase activity	Biological Process		2
GO:0043409	negative regulation of MAPK cascade	Biological Process		5
GO:0043506	regulation of JUN kinase activity	Biological Process		1
GO:0050906	detection of stimulus involved in sensory perception	Biological Process		1
GO:0005509	calcium ion binding	Molecular Function		124
GO:0005506	iron ion binding	Molecular Function		20
GO:0004722	protein serine/threonine phosphatase activity	Molecular Function	TAS[9326663]	8
GO:0001917	photoreceptor inner segment	Cellular Component		5
GO:0001750	photoreceptor outer segment	Cellular Component		8

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with PPEF2 (count: 0)

Genes shared at least 2 KEGG pathways with PPEF2 (count: 0)

View in gBrowse

Region: chr4:76781001..76823724 View in gBrowse