ADHDgene Database

Gene Report

Basic Info

Approved Symbol	NLRP10
Previous Symbol	NALP10
Symbol Alias	NOD8, PAN5, Pynod, CLR11.1
Approved Name	NLR family, pyrin domain containing 10
Previous Name	NACHT, leucine rich repeat and PYD containing 10
Name Alias	nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 10
Location	11p15.4
Position	chr11:7980971-7986973, -
External Links	HGNC: 21464 Entrez Gene: 338322 Ensembl: ENSG00000182261 UCSC: uc001mfv.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Elia[2010]_144	chr11:7800349-7938670 (NCBI Build 35 (hg17))	138322	11p15.4	Deletion (hemizygous)	Maternal

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 12)

ID	Name	Type	No. of Genes in ADHDgene
GO:2000778	positive regulation of interleukin-6 secretion	Biological Process	2
GO:0050832	defense response to fungus	Biological Process	3
GO:0050829	defense response to Gram-negative bacterium	Biological Process	7
GO:2000484	positive regulation of interleukin-8 secretion	Biological Process	2
GO:2000318	positive regulation of T-helper 17 type immune response	Biological Process	2
GO:0019897	extrinsic to plasma membrane	Cellular Component	3
GO:0035397	helper T cell enhancement of adaptive immune response	Biological Process	1
GO:0036336	dendritic cell migration	Biological Process	1
GO:0045087	innate immune response	Biological Process	54
GO:0002827	positive regulation of T-helper 1 type immune response	Biological Process	3
GO:0005524	ATP binding	Molecular Function	228
GO:0005737	cytoplasm	Cellular Component	690

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with NLRP10 (count: 1)

Gene Symbol	Pathway Count	Pathway List
PYCARD	5	positive regulation of interleukin-6 secretion; defense response to Gram-negative bacterium; positive regulation of interleukin-8 secretion; innate immune response; cytoplasm;

Genes shared at least 2 KEGG pathways with NLRP10 (count: 0)

View in gBrowse

Region: chr11:7980971..7986973 View in gBrowse