ADHDgene Database

Gene Report

Basic Info

Approved Symbol	EEF2K
Symbol Alias	eEF-2K
Approved Name	eukaryotic elongation factor-2 kinase
Location	16p12
Position	chr16:22217592-22300066, +
External Links	HGNC: 24615 Entrez Gene: 29904 Ensembl: ENSG00000103319 UCSC: uc002dki.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV; Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Williams[2010]_26	chr16:21851681-22651534 (NCBI Build 36.1 (hg18))	751397	16p12.1	Loss

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
16p12.3-12.2	chr16:16800000-24200000	1 (1/0/0)

Gene related GO terms (count: 12)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0008135	translation factor activity, nucleic acid binding	Molecular Function	TAS[9144159]	3
GO:0008286	insulin receptor signaling pathway	Biological Process		32
GO:0031952	regulation of protein autophosphorylation	Biological Process		1
GO:0046777	protein autophosphorylation	Biological Process	IDA[9144159]	23
GO:0004672	protein kinase activity	Molecular Function	TAS[9144159]	27
GO:0004686	elongation factor-2 kinase activity	Molecular Function	IDA[9144159]	1
GO:0005509	calcium ion binding	Molecular Function		124
GO:0005516	calmodulin binding	Molecular Function	IDA[9144159]	32
GO:0005524	ATP binding	Molecular Function		228
GO:0005737	cytoplasm	Cellular Component	TAS[9144159]	690
GO:0005829	cytosol	Cellular Component		447
GO:0006414	translational elongation	Biological Process	TAS[9144159]	16

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with EEF2K (count: 2)

Gene Symbol	Pathway Count	Pathway List
PAK1	5	protein autophosphorylation; protein kinase activity; ATP binding; cytoplasm; cytosol;
SMG1	5	protein autophosphorylation; protein kinase activity; ATP binding; cytoplasm; cytosol;

Genes shared at least 2 KEGG pathways with EEF2K (count: 0)

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Region: chr16:22217592..22300066 View in gBrowse