ADHDgene Database

Gene Report

Basic Info

Approved Symbol	COLEC12
Symbol Alias	SRCL, CL-P1, SCARA4
Approved Name	collectin sub-family member 12
Location	18pter-p11.3
Position	chr18:319355-500729, -
External Links	HGNC: 16016 Entrez Gene: 81035 Ensembl: ENSG00000158270 UCSC: uc002kkm.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Elia[2010]_201	chr18:362041-429089 (NCBI Build 35 (hg17))	67049	18p11.32	Deletion (hemizygous)	Paternal

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 13)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0051260	protein homooligomerization	Biological Process	NAS[11564734]	34
GO:0030169	low-density lipoprotein particle binding	Molecular Function	IDA[11564734]	5
GO:0016021	integral to membrane	Cellular Component	TAS[11162630]	845
GO:0046872	metal ion binding	Molecular Function		170
GO:0045087	innate immune response	Biological Process	TAS[11564734]	54
GO:0006952	defense response	Biological Process	TAS[11162630]	5
GO:0006910	phagocytosis, recognition	Biological Process	IDA[11564734]	1
GO:0009756	carbohydrate mediated signaling	Biological Process	NAS[11564734]	1
GO:0008329	pattern recognition receptor activity	Molecular Function	IDA[11564734]	2
GO:0002221	pattern recognition receptor signaling pathway	Biological Process	IDA[11564734]	2
GO:0005044	scavenger receptor activity	Molecular Function	TAS[11162630]	11
GO:0005534	galactose binding	Molecular Function	NAS[11564734]	1
GO:0005581	collagen	Cellular Component		7

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa04145	Phagosome	32	Phagocytosis is the process of taking in relatively large pa...... Phagocytosis is the process of taking in relatively large particles by a cell, and is a central mechanism in the tissue remodeling, inflammation, and defense against infectious agents. A phagosome is formed when the specific receptors on the phagocyte surface recognize ligands on the particle surface. After formation, nascent phagosomes progressively acquire digestive characteristics. This maturation of phagosomes involves regulated interaction with the other membrane organelles, including recycling endosomes, late endosomes and lysosomes. The fusion of phagosomes and lysosomes releases toxic products that kill most bacteria and degrade them into fragments. However, some bacteria have strategies to escape the bactericidal mechanisms associated with phagocytosis and survive within host phagocytes. More...

Genes shared at least 5 GO terms with COLEC12 (count: 0)

Genes shared at least 2 KEGG pathways with COLEC12 (count: 0)

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Region: chr18:319355..500729 View in gBrowse