ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Other Variant Report

Basic Info

Name	HLA-DRB1_alleles01-10
Type	HLA-DRB1 alleles
Related Gene	HLA-DRB1
No. of Study	2 (significant: 1; non-significant 1; trend: 0)

Variant related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Aureli A, 2008	allele 1-10		Fisher exact probability test P-value=0.45, OR=0.61 for DRB1...... Fisher exact probability test P-value=0.45, OR=0.61 for DRB101, Fisher exact probability test P-value=0.34, OR=1.59 for DRB102, Fisher exact probability test P-value=0.81, OR=0.84 for DRB103, Fisher exact probability test P-value=0.001, corrected P-value=0.01, OR=4.81 for DRB104, Fisher exact probability test P-value=0.03, OR=0.51 for DRB105, Fisher exact probability test P-value=0.71, OR=0.85 for DRB106, Fisher exact probability test P-value=0.28, OR=1.57 for DRB107, Fisher exact probability test P-value=0.70, OR=1.36 for DRB108 More...	HLA-DR4 frequencies of the ADHD group were significantly dif...... HLA-DR4 frequencies of the ADHD group were significantly different from controls, and frequencies of other HLA-DRB1 alleles did not differ significantly More...	Significant
Payton A, 2003	allele 1-10		allelic TDT simulated global P-value=0.16, X²=10....... allelic TDT simulated global P-value=0.16, X²=10.7 for the full sample, allelic TDT simulated global P-value=0.13, X²=11.31 for the complete trios; allelic TDT simulated global P-value=0.86, X²=0.03 for DRB01, allelic TDT simulated global P-value=0.25, X²=1.22 for DRB04 in the full sample; OR=1.1 for DRB01, OR=1.0 for DRB04 in the case-control analysis More...	no preferential transmission of any allele was noted and the...... no preferential transmission of any allele was noted and the case-control findings were also negative More...	Non-significant