Gene Report

Gene: RAC1     Link to MethyView
Summary
Gene symbol RAC1
Alias MGC111543, MIG5, P21-RAC1, RAC1, TC-25
Cytogenetic Location 7p22
Type KNOWN
Property protein_coding
Description Ras-related C3 botulinum toxin substrate 1 (p21-Rac1) (Ras-like protein TC25) (Cell migration-inducing gene 5 protein) [MIG5]
External Links
   Ensembl ENSG00000136238
   OMIM 602048
   mRNA NM_018890.2 NM_006908.3 NM_198829.1
   SwissProt P63000
 
 
Genomic Regions, Transcripts and Proteins
Gene Structure <0...275>, <12717...12788>, <17429...17546>, <24167...24223>, <25631...25693>, <27373...27532>, <27821...29469>
Ensembl Transcript ENST00000356142
Ensembl Protein ENSP00000348461
 
Gene Structure <0...275>, <12717...12788>, <17429...17546>, <25631...25693>, <27373...27532>, <27821...29469>
Ensembl Transcript ENST00000348035
Ensembl Protein ENSP00000258737
Gene Ontology GO:0007264 IEA Generated via Q969Q5
GO:0005525 IEA Generated via Q969Q5
GO:0005515 IPI Generated via P54259
GO:0003924 TAS Generated via O95716
GO:0000166 IEA Generated via Q9Y2A5
GO:0005622 IEA Generated via Q9Y2A4
GO:0048261 TAS Generated via P63000
GO:0035025 TAS Generated via Q8N0Z2
GO:0031529 TAS Generated via P53365
GO:0030041 TAS Generated via O43182
GO:0030032 IMP Generated via P53365
 
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DNA methylation and CGIs
Gene MethyCancer Type Candidate cancer gene with experimental methylation data
Link to MethyView
 
Mutations
ID 4720672
Nucleotide 1761bp 3' of STP C>T
Type known SNP
Source CGAP
 
ID 702484
Nucleotide IVS4+261C>G
Type known SNP
Source CGAP
 
ID 836554
Nucleotide 3157bp 3' of STP C>T
Type known SNP
Source CGAP
 
ID 836551
Nucleotide IVS7+141G>C
Type known SNP
Source CGAP
 
ID 3729790
Nucleotide IVS3+40G>A
Type known SNP
Source CGAP
 
ID 3729796
Nucleotide IVS7+12T>C
Type known SNP
Source CGAP
 
ID 6967221
Nucleotide IVS3-464G>A
Type known SNP
Source CGAP
 
ID 6463554
Nucleotide IVS4-492G>C
Type known SNP
Source CGAP
 
ID 2303364
Nucleotide IVS7+30T>C
Type known SNP
Source CGAP
 
Pathway
BIOCARTA BCR Signaling Pathway Link to BIOCARTA
 
BIOCARTA Agrin in Postsynaptic Differentiation Link to BIOCARTA
 
BIOCARTA Ras Signaling Pathway Link to BIOCARTA
 
BIOCARTA Influence of Ras and Rho proteins on G1 to S Transition Link to BIOCARTA
 
BIOCARTA Links between Pyk2 and Map Kinases Link to BIOCARTA
 
BIOCARTA Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling Link to BIOCARTA
 
BIOCARTA Tumor Suppressor Arf Inhibits Ribosomal Biogenesis Link to BIOCARTA
 
BIOCARTA fMLP induced chemokine gene expression in HMC-1 cells Link to BIOCARTA
 
BIOCARTA p38 MAPK Signaling Pathway Link to BIOCARTA
 
BIOCARTA Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration Link to BIOCARTA
 
BIOCARTA Transcription factor CREB and its extracellular signals Link to BIOCARTA
 
BIOCARTA Role of MAL in Rho-Mediated Activation of SRF Link to BIOCARTA
 
BIOCARTA Rac 1 cell motility signaling pathway Link to BIOCARTA
 
BIOCARTA MAPKinase Signaling Pathway Link to BIOCARTA
 
BIOCARTA Ras-Independent pathway in NK cell-mediated cytotoxicity Link to BIOCARTA
 
BIOCARTA How does salmonella hijack a cell Link to BIOCARTA
 
BIOCARTA uCalpain and friends in Cell spread Link to BIOCARTA
 
BIOCARTA Phospholipids as signalling intermediaries Link to BIOCARTA
 
BIOCARTA T Cell Receptor Signaling Pathway Link to BIOCARTA
 
BIOCARTA Phosphoinositides and their downstream targets. Link to BIOCARTA
 
BIOCARTA Y branching of actin filaments Link to BIOCARTA