Gene Report

Gene: MAP3K7     Link to MethyView
Summary
Gene symbol MAP3K7
Alias MAP3K7, TAK1, TGF1A
Cytogenetic Location 6q16.1-q16.3
Type KNOWN
Property protein_coding
Description Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) [TAK1]
External Links
   Ensembl ENSG00000135341
   OMIM 602614
   UniGene Hs.644143
   mRNA NM_145333.1 NM_145332.1 NM_145331.1 NM_003188.2
   SwissProt O43318
 
Expression
Expresstion pancreatic, mammary, whole, liver, head, vascular, brain, gastrointestinal, cervix, colon, muscle, placenta, pooled, uncharacterized, synovium, cerebellum, ovary, cartilage, bone, stomach, uterus, kidney, skin, cerebrum, lymphoreticular, peripheral, prostate, embryonic, lung, lymph, thyroid, nervous, testis, adipose, eye, thymus, ear, genitourinary, spleen
Related library Link
 
Genomic Regions, Transcripts and Proteins
Gene Structure <0...998>, <2764...2879>, <3575...3636>, <7995...8100>, <20654...20718>, <31575...31704>, <32364...32494>, <34785...36496>, <37775...37781>
Ensembl Transcript ENST00000369320
Ensembl Protein ENSP00000358326
 
Gene Structure <0...3108>, <5685...5746>, <10105...10210>, <22764...22828>, <33685...33814>, <34474...34604>, <36895...36976>, <38476...38606>, <39885...40013>, <42927...43051>, <46503...46641>, <48049...48094>, <54985...55050>, <58124...58234>, <73191...73316>
Ensembl Transcript ENST00000369327
Ensembl Protein ENSP00000358333
Gene Ontology GO:0005524 IEA Generated via Q59F24
GO:0016740 IEA Generated via Q86UN3
GO:0006468 IEA Generated via Q59F24
GO:0000166 IEA Generated via Q9Y2A5
GO:0004674 IEA Generated via Q9Y2A5
GO:0004713 IEA Generated via Q59F24
 
Gene Structure <0...3108>, <4874...4989>, <5685...5746>, <10105...10210>, <22764...22828>, <33685...33814>, <34474...34604>, <36895...36976>, <38476...38606>, <39885...40013>, <42927...43051>, <46503...46641>, <48049...48094>, <54985...55050>, <58124...58234>, <73191...73472>
Ensembl Transcript ENST00000369332
Ensembl Protein ENSP00000358338
 
Gene Structure <0...3108>, <4874...4989>, <5685...5746>, <10105...10210>, <22764...22828>, <30979...31059>, <33685...33814>, <34474...34604>, <36895...36976>, <38476...38606>, <39885...40013>, <42927...43051>, <46503...46641>, <48049...48094>, <54985...55050>, <58124...58234>, <73191...73472>
Ensembl Transcript ENST00000369329
Ensembl Protein ENSP00000358335
Gene Ontology GO:0000165 IEA Generated via P49137
GO:0007179 TAS Generated via O60383
GO:0043066 IEA Generated via P11309
GO:0001525 IEA Generated via Q5T7F3
GO:0046330 IEA Generated via Q9H2K8
GO:0043123 IEA Generated via P25942
GO:0004674 IEA Generated via Q9Y2A5
GO:0004709 TAS Generated via Q99683
GO:0000166 IEA Generated via Q9Y2A5
GO:0000287 IEA Generated via Q9Y251
GO:0001841 IEA from Mus musculus translation ENSMUSP00000054428
GO:0016740 IEA Generated via Q86UN3
GO:0007252 IEA Generated via O15111
GO:0006468 IEA Generated via Q59F24
GO:0005515 IPI Generated via P54259
GO:0005524 IEA Generated via Q59F24
 
Gene Structure <0...3108>, <5685...5746>, <10105...10210>, <22764...22828>, <30979...31059>, <33685...33814>, <34474...34604>, <36895...36976>, <38476...38606>, <39885...40013>, <42927...43051>, <46503...46641>, <48049...48094>, <54985...55050>, <58124...58234>, <73191...73310>
Ensembl Transcript ENST00000369325
Ensembl Protein ENSP00000358331
 
Click for MenuClick for MenuClick for MenuClick for MenuClick for MenuClick for Menu

DNA methylation and CGIs
Gene MethyCancer Type Candidate cancer gene with experimental methylation data
Link to MethyView
 
Pathway
BIOCARTA NF-kB Signaling Pathway Link to BIOCARTA
 
BIOCARTA Signal transduction through IL1R Link to BIOCARTA
 
BIOCARTA NFkB activation by Nontypeable Hemophilus influenzae Link to BIOCARTA
 
BIOCARTA Toll-Like Receptor Pathway Link to BIOCARTA
 
BIOCARTA p38 MAPK Signaling Pathway Link to BIOCARTA
 
BIOCARTA ALK in cardiac myocytes Link to BIOCARTA
 
KEGG MAPK signaling pathway Link to KEGG
 
BIOCARTA MAPKinase Signaling Pathway Link to BIOCARTA
 
KEGG T cell receptor signaling pathway Link to KEGG
 
KEGG Adherens junction Link to KEGG
 
BIOCARTA WNT Signaling Pathway Link to BIOCARTA
 
BIOCARTA TNFR1 Signaling Pathway Link to BIOCARTA
 
KEGG Gap junction Link to KEGG
 
KEGG Apoptosis Link to KEGG
 
KEGG Wnt signaling pathway Link to KEGG
 
KEGG GnRH signaling pathway Link to KEGG
 
BIOCARTA FAS signaling pathway ( CD95 ) Link to BIOCARTA
 
BIOCARTA TGF beta signaling pathway Link to BIOCARTA
 
KEGG Toll-like receptor signaling pathway Link to KEGG
 
BIOCARTA Thrombin signaling and protease-activated receptors Link to BIOCARTA
 
KEGG Epithelial cell signaling in Helicobacter pylori infection Link to KEGG