Cancer Report

Cancer : t(9;14)(q34;q32)
Summary
Cancer Name t(9;14)(q34;q32)
 
Clinics and Pathology
Disease T cell acute lymhoblastic leukemia (T-ALL)
Epidemiology only 1 case to date: a 16 yr old female patient
Prognosis yet unknown; the patient was in complete remission at 15 mths+.
 
Related Genes
Gene Symbol EML1
Description gene was mapped within Usher syndrome type 1a locusprotein is very similar to the echinoderm microtubule-associated protein
 
Gene Symbol ABL1
Description tyrosine kinase
 
Cytogenetics
Cytogenetics Molecular FISH with 5?ABL1 probe (RP11-57C19) and 3?ABL1 probe (RP11-83J21) resulted in a split signal
 
Bibliography
Title Fusion of EML1 to ABL1 in T-cell acute lymphoblastic leukemia with cryptic t(9;14)(q34;q32).
Authors De Keersmaecker K, Graux C, Odero MD, Mentens N, Somers R, Maertens J, Wlodarska I, Vandenberghe P, Hagemeijer A, Marynen P, Cools J.
Citations Blood 2005; 105: 4849-4852.
PubMedID 15713800
 
Source and Citation
Source Atlas of Genetics and Cytogenetics in Oncology and Haematology
Citation De Keersmaecker K, Huret JL . t(9;14)(q34;q32). Atlas Genet Cytogenet Oncol Haematol. July 2005 .
URL : http://AtlasGeneticsOncology.org/Anomalies/t0914q34q32ID1399.html
URL http://AtlasGeneticsOncology.org/Anomalies/t0914q34q32ID1399.html